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We are in the midst of a transformation of medical technology, driven in large part by parallel exponential changes in three areas of technology: genomics, which provides high-resolution data about the molecular composition of our bodies; data science and AI, which allow us to identify patterns in these data; and therapeutics, which provides increasingly precise ways to intervene in human biology to prevent or cure disease. In combination, these technologies define the emerging field of genomic medicine, which has already had a profound impact on the diagnosis of genetic disorders and the treatment of cancer, and has the potential to improve virtually all areas of healthcare. However, these technologies also create new challenges, including maintaining high quality in an era of rapid change; potential increases in the cost of healthcare; and equity of access and impact. Prof MacArthur will outline the potential of the field of genomic medicine and summarise the challenges ahead, acknowledging that resolving them will require a multi-pronged strategy across research, healthcare systems, policy, and society.
